October is Breast Cancer Awareness Month – Yahoo Finance

Posted By on October 30, 2021

23andMe Scientist and Customer Discuss How Direct-to-Consumer Genetic Health Tests Can Make an Impact on Health

New York, New York --News Direct-- YourUpdateTV

BRCA1 and BRCA2 are genes that have been found to impact a persons chances of developing certain cancers, including breast, ovarian and prostate cancer. Recently, 23andMe scientist, Ruth Tennen, and customer, Gina Burris, participated in a nationwide satellite media tour to discuss the first and only FDA-authorized, direct-to-consumer test that detects select BRCA1/BRCA2 variants*.

A video accompanying this announcement is available at: https://youtu.be/ziqp10R_j_A

23andMe Scientist and Customer Discuss How Direct-to-Consumer Genetic Health Tests Can Make an Impact on Health

The genes are called BRCA because the link between these genes and breast cancer was discovered first. The genes themselves do not cause cancer. They actually help prevent it by repairing DNA breaks that can lead to cancer. Sometimes, changes in the BRCA genes occur that prevent them from functioning properly. These changes are called genetic variants or mutations. Variants in the BRCA1 and BRCA2 genes can be passed down through families, increasing the risk of developing certain cancers.

Many people with a BRCA variant, both women and men, are unaware of their risk and what they can do about it. While it is true that having certain BRCA variants can increase a persons risk of developing cancer, most cases of breast, ovarian and prostate cancers arent caused by inherited BRCA variants. And not every individual who inherits a BRCA variant will develop cancer.

23andMe offers a genetic test for three variants in the BRCA1 and BRCA2 genes to its Health + Ancestry Service customers. This genetic test detects three selected variants in the BRCA1 and BRCA2 genes BRCA1 185delAG; BRCA1 5382insC; and BRCA2 6174delT that are among the most studied and best understood. These three variants are most common in people of Ashkenazi Jewish descent. (They can be found in people of other ethnicities, though this is rare.) If you have one of these three variants, you have an increased risk of developing certain cancers.

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For more information, visit 23andMe.com/brca

*The 23andMe PGS test uses qualitative genotyping to detect select clinically relevant variants in the genomic DNA of adults from saliva for the purpose of reporting and interpreting genetic health risks, including the 23andMe PGS Genetic Health Risk Report for BRCA1/BRCA2 (Selected Variants). Your ethnicity may affect the relevance of each report and how your genetic health risk results are interpreted. The test is not intended to diagnose any disease and does not describe a persons overall risk of developing any type of cancer. It is not intended to tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication, how much of a medication you should take, or determine any treatments. Warnings & Limitations: The 23andMe PGS Genetic Health RIsk Report for BRCA1/BRCA2 (Selected Variants) is indicated for reporting of the 185delAG and 5382insC variants in the BRCA1 gene and the 6174delT variant in the BRCA2 gene. The report describes if a woman is at increased risk of developing breast and ovarian cancer, and if a man is at increased risk of developing breast cancer or may be at increased risk of developing prostate cancer. The three variants included in this report are most common in people of Ashkenazi Jewish descent and do not represent the majority of BRCA1/BRCA2 variants in the general population. This report does not include variants in other genes linked to hereditary cancers and the absence of variants included in this report does not rule out the presence of other genetic variants that may impact cancer risk. The PGS test is not a substitute for visits to a healthcare professional for recommended screenings or appropriate follow-up. Results should be confirmed in a clinical setting before taking any medical action.

About Gina Burris:

Gina Marie Burris lives in a small riverside community in western Pennsylvania. She is a childrens book author and blogger. At the age of 46 with no known family history of breast or ovarian cancer Gina discovered (via a 23andMe health report) she carries a BRCA variant . After making this discovery, Gina worked closely with a team of medical professionals and made the decision to take a preventative path. Since November 2020 Gina has undergone a bi-lateral salpingo-oophorectomy and double mastectomy straight to reconstruction. After finding refuge in the stories of survivors, previvors and patients, Gina felt compelled to share her own story, so she turned to the place she feels most comfortable, her keyboard. Ginas blog http://www.rivergirlreflections.com follows her journey from early in the process through today. She has found a way to bring truth, grace, and a little humor to a serious situation. Gina aspires to bring awareness to what life with a BRCA variant looks like in todays world. She has a passion for speaking freely about her experience and strives to be a small part of an educational community which shifts the wording in some common breast cancer awareness conversations.

About Ruth Tennen:

As a product scientist at 23andMe, Ruth develops new genetic health reports with the goal of helping 23andMe customers access, understand, and benefit from the human genome. Ruth received her bachelor's degree in molecular biology from Princeton University and her Ph.D. in cancer biology from Stanford University. Before joining 23andMe, she served as a science policy fellow at the State Department, helping promote science education and entrepreneurship in Africa, and as a lecturer at Stanford, teaching courses on experimental design, bioethics, and cancer. Ruth loves learning about and talking about science, and throughout her career, she has worked to inspire budding scientists by mentoring and teaching students at local schools, hospitals, and museums.

About YourUpdateTV:

YourUpdateTV is a social media video portal for organizations to share their content. It includes separate channels for Health and Wellness, Lifestyle, Media and Entertainment, Money and Finance, Social Responsibility, Sports and Technology.


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